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KMID : 1040020230140020068
International Journal of Pain
2023 Volume.14 No. 2 p.68 ~ p.78
Prognostic Factors Affecting Therapeutic Efficacy of Intradiscal Steroid Injection in Patients with Chronic Discogenic Low Back Pain
Kim Nack-Hwan

Lee Sang-Heon
Abstract
Background: This study aims to find out which clinical and radiologic factors affect how well intradiscal steroid injections (ISI) work for patients with discogenic lower back pain (DLBP).

Methods: We looked back at the clinical records and radiologic images of 60 patients with DLBP, confirmed using a provocation discography. They all received ISI between May 2011 and December 2014 at a single clinic. We evaluated the degeneration grade of the discs, whether they showed a high intensity zone (HIZ), and Modic changes in the adjacent vertebral bodies. Clinical outcome was assessed by visual analogue scale (VAS).

Results: Six months post ISI, patients with pain duration < 6 months (P = 0.02), type I Modic change (P = 0.048), and the presence of HIZ (P = 0.046) exhibited significantly greater reductions in the VAS. Multivariate logistic regression analysis highlighted three factors linked to successful outcomes after ISI: pain duration < 6 months (OR = 8.695, P = 0.007), type 1 Modic change (OR = 3.382, P = 0.021), and the presence of HIZ (OR = 4.902, P = 0.015).

Conclusions: We found three important factors through statistics: pain for < 6 months, Type I Modic changes, and the presence of a HIZ. By carefully choosing patients with these characteristics, considering the risks of treatment, and factors predicting outcomes, we can anticipate better results in treating DLBP.
KEYWORD
chronic discogenic pain, intradiscal steroid injection, prognosis, provocation discography
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