KMID : 1040020230140020068
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International Journal of Pain 2023 Volume.14 No. 2 p.68 ~ p.78
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Prognostic Factors Affecting Therapeutic Efficacy of Intradiscal Steroid Injection in Patients with Chronic Discogenic Low Back Pain
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Kim Nack-Hwan
Lee Sang-Heon
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Abstract
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Background: This study aims to find out which clinical and radiologic factors affect how well intradiscal steroid injections (ISI) work for patients with discogenic lower back pain (DLBP).
Methods: We looked back at the clinical records and radiologic images of 60 patients with DLBP, confirmed using a provocation discography. They all received ISI between May 2011 and December 2014 at a single clinic. We evaluated the degeneration grade of the discs, whether they showed a high intensity zone (HIZ), and Modic changes in the adjacent vertebral bodies. Clinical outcome was assessed by visual analogue scale (VAS).
Results: Six months post ISI, patients with pain duration < 6 months (P = 0.02), type I Modic change (P = 0.048), and the presence of HIZ (P = 0.046) exhibited significantly greater reductions in the VAS. Multivariate logistic regression analysis highlighted three factors linked to successful outcomes after ISI: pain duration < 6 months (OR = 8.695, P = 0.007), type 1 Modic change (OR = 3.382, P = 0.021), and the presence of HIZ (OR = 4.902, P = 0.015).
Conclusions: We found three important factors through statistics: pain for < 6 months, Type I Modic changes, and the presence of a HIZ. By carefully choosing patients with these characteristics, considering the risks of treatment, and factors predicting outcomes, we can anticipate better results in treating DLBP.
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KEYWORD
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chronic discogenic pain, intradiscal steroid injection, prognosis, provocation discography
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