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KMID : 1040320240310010136
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Pediatric Infection & Vaccine
2024 Volume.31 No. 1 p.136 ~ p.139
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Rhabdomyolysis Following SARS-CoV-2 Infection in Children: A Case Report and Systematic Review
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Oh Na-Won
Gwag Si-Hwa
Cho Kyu-Sik
Choe Young-June
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Abstract
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Rhabdomyolysis is a syndrome that causes various complications due to the release of substances from muscle cells, often associated with preceding infectious diseases. We report the case of a 7-year-old Korean boy with recent severe acute respiratory syndrome coronavirus 2 infection, presenting with fever, chills, and generalized body aches, diagnosed as rhabdomyolysis. Additionally, we conducted a systematic review with the aim of delineating the disease spectrum, treatment, and outcomes. We identified seven reports that met the inclusion criteria. Among the cases, 5 had fever, with creatine kinase levels ranging from 3,717 and 274,664 IU/L. Two individuals received treatment in intensive care unit, 2 underwent renal replacement therapy, and 1 case has deceased. For children with coronavirus disease 2019 infection and muscle pain, a thorough examination of urine color and an assessment of muscle enzymes through blood tests can help diagnose and treat rhabdomyolysis, a condition that might otherwise be overlooked.
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KEYWORD
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Rhabdomyolysis, Myositis, COVID-19, SARS-CoV-2
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