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KMID : 1044320200220020112
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Annals of Clinical Neurophysiology
2020 Volume.22 No. 2 p.112 ~ p.116
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Overlap syndrome of Miller-Fisher syndrome/Pharyngeal-Cervical-Brachial variant-Guillain Barre Syndrome with anti-ganglioside complex antibodies
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Lee Suk-Yoon
Oh Seong-Il
Huh So-Young
Shin Kyong-Jin
Kim Jong-Kuk
Yoon Byeol-A
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Abstract
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Guillain-Barre syndrome (GBS) and Miller Fisher syndrome (MFS) can present with overlapping features. A 56-year-old female developed ptosis and diplopia after an upper respiratory infection, and presented with facial palsy, dysarthria, brachial weakness, ataxia, and areflexia. Mild weakness of both legs appeared after a few days. Anti-ganglioside complex antibody were positive to IgG GM1/GQ1b and GQ1b/sulfatide antibodies. The present case suggests that the manifestation of overlap between MFS/PCB variants and GBS could be caused by antiganglioside complex antibodies.
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KEYWORD
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Guillain-Barre syndrome, Miller Fisher syndrome, Pharyngeal-cervical-brachial variant, Antibodies, Ganglioside, Anti-ganglioside complex
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