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KMID : 1100120170240030155
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대한골대사학회지
2017 Volume.24 No. 3 p.155 ~ p.159
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Gestational Diabetes Mellitus, Fetal Growth and Vitamin D
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Yoon Hyun-Koo
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Abstract
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Vitamin D is an important secosteroid hormone in skeletal and non-skeletal systems. Vitamin D has relevance to muscle and immune function, hypertension, diabetes mellitus, cancer, and pregnancy because vitamin D receptors (VDR) are present in many non-skeletal tissues. Vitamin D acts on target tissues via the binding of its active form to VDR. As vitamin D affects not only bone metabolism but also glucose metabolism, vitamin D deficiency may affect the development of gestational diabetes mellitus and fetal growth. Although vitamin D deficiency is prevalent during pregnancy, there are conflicting reports on the effect of vitamin D deficiency on pregnancy complications, such as fetal growth restriction and gestational diabetes. This article reviews published papers on the effects of vitamin D on gestational diabetes and fetal growth.
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KEYWORD
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Diabetes, Gestational, Fetal development, Vitamin D
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