KMID : 1100120210280020101
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´ëÇÑ°ñ´ë»çÇÐȸÁö 2021 Volume.28 No. 2 p.101 ~ p.113
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Application of the Trabecular Bone Score in Clinical Practice
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Kong Sung-Hye
Hong Nam-Ki Kim Jin-Woo Kim Deog-Yoon Kim Jung-Hee
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Abstract
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The trabecular bone score (TBS) was introduced as an indirect index of trabecular microarchitecture, complementary to bone mineral density (BMD), and is derived using the same dual energy X-ray absorptiometry images. Recently, it has been approved for clinical use in Korea. Therefore, we conducted a comprehensive review to optimize the use of TBS in clinical practice. The TBS is an independent predictor of osteoporotic fractures in postmenopausal women and men aged >50 years. The TBS is potentially useful in monitoring the skeletal effects of anabolic agents but not of antiresorptive agents. In postmenopausal women with type 2 diabetes mellitus, the TBS assesses osteoporotic fracture risk not captured by BMD. However, high body mass index and soft tissue thickness can cause underestimation of the TBS; however, this limitation has been improved in recent versions of the TBS software. However, a high precision error and low reproducibility limit the use of TBS. This review may provide information on the application of the TBS in clinical practice based on reliable evidence.
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KEYWORD
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Cancellous bone, Hip fractures, Osteoporosis, Osteoporotic fractures
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