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KMID : 1100220070060020038
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Dementia and Neurocognitive Disorders
2007 Volume.6 No. 2 p.38 ~ p.41
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Anatomical Correlates of Comprehension and Repetition Areas: Manual Tracing Study
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Kim Geon-Ha
Jeong Jee-H
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Abstract
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Background: The brain area involved in language processing has long been fascinated the Neurologists. Even though anatomical imaging studies or autopsies have been used to define the area involved in each specific domain of language, the precise connections involved in comprehension to repetition are still unclear. To understand language network, we designed to manually trace the area of focal infarction in first-ever stroke patients manifesting aphasia to compare a specific comprehension defect type with a conduction defect type.
Material and Methods: The participants included 8 acute first-ever stroke patients with aphasia from April 2005 to June 2006. Five patients had a comprehension defect type (sensory) and three had a conduction defect type of aphasia. We assessed the patients’ symptomatic brain lesions with brain MRI and MR angiography and examined the language function using the Korean-Western Aphasia Battery (K-WAB) test, within 3 to 12 days of the stroke onset. Then we tried to correlate the specific type of aphasia with neuroanatomical locations by adding together manual drawings of the infarcted lesions drawn on translucent paper.
Results: There was little difference in anatomical lesion between comprehension defect type and conduction defect type of aphasia. However, almost all comprehension defect type of aphasia had larger size of infarct lesions involving superior temporal gyrus compared to the conduction defect type, which had more involvement in inferior parietal lobule.
Discussion: It is difficult to differentiate between comprehension and conduction types of aphasia just by anatomical location. However, the small sample size seemed to put a limitation on a meaningful outcome. Thus, further study including more study subjects and employing functional imaging such as single photon emission computed tomography (SPECT) and magnetic resonance imaging volumetry needs to be done.
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KEYWORD
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Language, Comprehension, Conduction, Anatomy, Brain MRI
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