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KMID : 1100720130330020141
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Annals of Laboratory Medicine
2013 Volume.33 No. 2 p.141 ~ p.144
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CTX-M-55-Type Extended-Spectrum β-lactamase- Producing Shigella sonnei Isolated from a Korean Patient Who Had Travelled to China
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Lee Won-Mok
Yong Dong-Eun
Jeong Seok-Hoon
Lee Kyung-Won
Chong Yun-Sop
Chung Hae-Sun
Lee Hyuk-Min
Yum Jong-Hwa
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Abstract
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We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3˚C). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.
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KEYWORD
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CTX-M-55, Shigella sonnei, ESBL
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