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KMID : 1101420220540020110
Korean Journal of Clinical Laboratory Science
2022 Volume.54 No. 2 p.110 ~ p.118
Frequency of Candida Strains Isolated from Candidiasis Patients at A Tertiary Hospital over the Last 10 Years
Hwang Yu-Yean

Kang On-Kyun
Park Chang-Eun
Hong Sung-No
Kim Young-Kwon
Huh Hee-Jae
Lee Nam-Yong
Abstract
Candidemia is a major cause of nosocomial infections resulting in increased morbidity and mortality. It remains a serious risk in inpatients and increases medical treatment costs. From 2009 to 2018, Candida strains (3,533) isolated from blood culture tests at the S Hospital were analyzed according to the period, year, sex, age, ward, etc. During the entire period, 54,739 of 717,996 blood culture tests showed a positive rate (7.6%) and the Candida isolation rate was 3,533 (6.4%) out of 1,036 patients. Among the Candida isolates, C. albicans was most common (33.8%), followed by C. tropicalis (28.6%), C. glabrata (19.8%), C. parapsilosis (7.8%), and C. krusei (4.0%). In early (2009¡­2013)/late (2014¡­2018) isolation, C. tropicalis decreased by 3.8% and C. glabrata increased by 3.4%. After 50 years of age, the higher the separation frequency. C. parapsilosis (31.3%) in 1¡­10s, C. tropicalis (30.3%) and C. glabrata (27.6%) in 41¡­50s, and C. tropicalis (28.6%) in 80s are relatively frequent. has been separated C. krusei was isolated in a relatively high proportion from females (60.9%). Therefore, a systematic and continuous nosocomial infection control system should be established for appropriate treatment as per antifungal treatment guidelines. The system should continuously monitor the distribution of Candida species and provide rapid identification results.
KEYWORD
Blood culture, Candidemia, Candida bloodstream infections, Candida species, Non albicans Candida species
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