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KMID : 1101620210320020080
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Perinatology
2021 Volume.32 No. 2 p.80 ~ p.84
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Case Report of Pregnancy Induced Atypical Hemolytic-uremic Syndrome
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Jeon Eun-Hye
Lee Sul
Kim So-Hee
Yoon Hyung-Joon
Joo Jong-Kil
Kim Seung-Chul
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Abstract
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Pregnancy-associated atypical hemolytic-uremic syndrome (p-aHUS) is a rare and fatal thrombotic microangiopathy characterized by hemolytic anemia, thrombocytopenia and acute renal injury during pregnancy. A pregnant woman with atypical symptoms of hemolytic-uremic syndrome (HUS) delivered a baby by cesarean delivery under suspicion of atypical hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome at 35 weeks of gestation. However, even after delivery, the patient's condition worsened. Following this, p-aHUS was diagnosed through as a result of ADAMTS13 activity. After several plasma exchanges (PEs) based on diagnosis, vital signs were stabilized and laboratory results were normalized. Herein, we report and review an unusual case of woman with complicated p-aHUS who recovered after PE.
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KEYWORD
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Atypical hemolytic-uremic syndrome, Plasma exchange, Thrombotic microangiopathy
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