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KMID : 1102020170470040218
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Applied Microscopy
2017 Volume.47 No. 4 p.218 ~ p.222
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The Nobel Prize in Chemistry 2017: High-Resolution Cryo-Electron Microscopy
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Chung Jae-Hee
Kim Ho-Min
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Abstract
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The 2017 Nobel Prize in Chemistry was awarded to the following three pioneers: Dr. Joachim Frank, Dr. Jacques Dubochet, and Dr. Richard Henderson. They all contributed to the development of a Cryo-electron microscopy (EM) technique for determining the high-resolution structures of biomolecules in solution, particularly without crystal and with much less amount of biomolecules than X-ray crystallography. In this brief commentary, we address the major advances made by these three Nobel laureates as well as the current status and future prospects of this Cryo-EM technique.
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KEYWORD
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High-resolution Cryo-electron microscopy, Nobel Prize, Biomolecule structure
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