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KMID : 1103720120660020117
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Journal of the Korean Society of Radiology
2012 Volume.66 No. 2 p.117 ~ p.122
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Usefulness of Apparent Diffusion Coefficient Values in the Nasopharynx and the Oropharynx: Differentiation of Benign and Malignant Lesions
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Kwon Hoon
Kim Hak-Jin
Sol Yu-Li
Lee Tae-Hong
Yeom Jeong-A
Kim Ah-Rong
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Abstract
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Purpose: In several previous studies, apparent diffusion coefficient (ADC) calculation was applied in the evaluation of head and neck tumors and is a promising technique for this application. As a result, we reevaluated the usefulness of ADC measurement with differentiation of benign and malignant pathology in the nasopharynx and oropharynx.
Materials and Methods : The study population consisted of 87 consecutive patients who had undergone routine nasopharyngeal and oropharyngeal MR imaging at our institution, which included diffusion weighted image and ADC map, with a clinically suspected primary tumor of nasopharynx and oropharynx. The mean ADC values in the benign and malignant groups were compared and the malignant group was divided into the lymphoma and carcinoma groups.
Results: A statistically significant difference in ADC values among the benign and malignant groups using independent samples t-test with a p < 0.001. The lymphoma and carcinoma groups were compared by the Man-Whitney U test, which revealed a statistically significant difference with a p = 0.002. When an ADC of 1.1 × 10-3 mm2/s was used to distinguish between benign and malignancy, accuracy was 85%.
Conclusion: ADC values were useful for distinguishing between benign and malignancy in the nasopharynx and oropharynx.
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KEYWORD
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MRI, Diffusion-Weighted Image, Nasopharynx, Oropharynx, Malignancy
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