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KMID : 1104820130010010029
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Journal of Digestive Cancer Research
2013 Volume.1 No. 1 p.29 ~ p.35
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Treatment Strategy of Intractable Peritoneal Carcinomatosis
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Jung Jae-Gu
Lim Yun-Jeong
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Abstract
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Peritoneal carcinomatosis (PC) is defined as the dissemination of cancer cells in the peritoneal cavity resulting in deposition of malignant cells onto parietal or visceral peritoneal surfaces, and is associated with malignant ascites. In general, PC has been treated similarly to metastatic cancers of the primary tumor, but associated with unfavorable outcomes as compared to other sites of metastatic disease from the same primary tumor origin. It has been known to have the median survival of only 3-6 months with supportive care alone. PC is an intractable problem to physicians because of its poor prognosis and limited treatment options. Recent studies have reported that a combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy improved survival in PC of colorectal cancer. This paper gives overviews of the characteristics, symptoms, prognosis, and diagnosis of PC and current treatment options on PC of stomach, colorectal, and unknown primary origin.
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KEYWORD
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Peritoneal neoplasms, Gastric cancer, Colorectal cancer, Treatment, Chemotherapy
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