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KMID : 1104820150030010017
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Journal of Digestive Cancer Research
2015 Volume.3 No. 1 p.17 ~ p.20
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Neoadjuvant Strategies for Pancreatic Cancer
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Ahn Dong-Won
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Abstract
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Pancreatic cancer is an aggressive tumor and only 10-20% patients are considered candidates for curative resection at diagnosis. While surgery remains the only chance for cure, prognosis is poor even after surgery due to high rate of recurrence. A complementary chemotherapy and radiotherapy in a multimodal approach has been attempted to improved prognosis after surgery. Since adjuvant chemotherapy has yielded an only modest outcome improvement, various neoadjuvant approaches with chemotherapy, chemoradiation, or chemotherapy followed by chemoradiation have been attempted. In this article, current knowledge of the various neoadjuvant approaches for pancreatic cancer will be reviewed and the role of the neoadjuvant strategies will be discussed.
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KEYWORD
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Pancreatic cancer, Neoadjuvant therapy, Resection rate
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