KMID : 1104820170050020086
|
|
Journal of Digestive Cancer Research 2017 Volume.5 No. 2 p.86 ~ p.90
|
|
Type 3 Gastric Neuroendocrine Neoplasm Clinical Features: A Multicenter Study in Korea
|
|
Lee Kyong-Joo
Kim Hee-Man Lee Sang-Kil Choi Ho-Sun Kim Jie-Hyun Park Seun-Ja Park Sung-Chul Jang Byung-Ik Jung Jin-Tae Jeon Tae-Joo Lee Jong-Hun Sung Jae-Kyu Park Se-Mi Kim Yoon-Jae Cho Jae-Hee
|
|
Abstract
|
|
|
Background: The aim of this study was to investigate clinicopathologic features of type 3 gastric neuroendocrine neoplasm (NEN) by treatment modality.
Methods: The Korean Society of Gastrointestinal Cancer conducted the Korean Gastroenteropancreatic Neuroendocrine Tumor Registry, a retrospective registry database of gastroenteropancreatic neuroendocrine tumors from 16 hospitals in Korea. The normal serum gastrin level range was defined as <100 pg/mL, and gastric NEN patients with normal gastrin level were selected for analysis.
Results: Among 358 patients with gastric NEN, 21 (5.9%) patients were classified with type 3 gastric NEN. The median age was 53 years (range 30-74). According to the WHO 2010 classification, 13 (61.9%) patients had grade 1, and 8 (38.1%) patients had grade 2 or 3. Endoscopic treatment was performed in 14 (66.7%) patients, and surgery was performed in 7 (33.3%) patients. The tumor size was smaller in the endoscopic treatment group than in the surgery group (0.6 cm vs 1.3 cm, p=0.006). After treatment, there was one recurrence in the surgery group.
Conclusion: In small size Type 3 gastric NEN, endoscopic treatment was associated with a good prognosis, compared to surgery. Thus, endoscopic treatment can be used an alternative modality in selected cases of type 3 gastric NEN.
|
|
KEYWORD
|
|
Stomach, Neuroendocrine neoplasm, Type 3, Endoscopic resection, Surgery
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|