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KMID : 1130320080510060640
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Korean Journal of Pediatrics
2008 Volume.51 No. 6 p.640 ~ p.645
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Clinical manifestations patterns of allergic disease in Korean children under the age of 6: multi-center study
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Kim Dong-Il
Park Yong-Mean
Rha Yeong-Ho
Choung Ji-Tae
Yang Hyeon-Jong
Pyun Bok-Yang
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Abstract
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Purpose: It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress.
Methods: Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire.
Results: A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease.
Conclusions: In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.
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KEYWORD
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Allergic march, Questionnaire, Multicenter study
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