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KMID : 1130320080510121320
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Korean Journal of Pediatrics
2008 Volume.51 No. 12 p.1320 ~ p.1323
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Epidemiologic study of Kawasaki disease in 6 months old and younger infants
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Park Yong-Won
Han Ji-Whan
Park In-Sook
Kim Chang-Hwi
Cha Sung-Ho
Ma Jae-Sook
Lee Joon-Sung
Kwon Tae-Chan
Lee Sang-Bum
Kim Chul-Ho
Lee Heung-Jae
Yun Yong-Soo
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Abstract
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Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age.
Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6 months of age were analyzed and compared with those of KD patients >6 months of age.
Results : A total of 1,739 patients ≤6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67:1. Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively.
Conclusion : Comparison of data from KD patients >6 months old with data from 1,739 KD patients ≤6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients.
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KEYWORD
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Mucocutaneous lymph node syndrome, Coronary aneurysm, Epidemiology, Infant
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