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KMID : 1130320090520101082
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Korean Journal of Pediatrics
2009 Volume.52 No. 10 p.1082 ~ p.1089
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Recent concepts on vitamin D in children and adolescents
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Yang Hye-Ran
Seo Jeong-Wan
Kim Yong-Joo
Kim Jae-Young
Ryoo Eell
Sim Jae-Geon
Yom Hye-Won
Chang Ju-Young
Jung Ji-A
Choi Kwang-Hae
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Abstract
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Vitamin D is an important fat-soluble vitamin that functions as a prohormone and affects bone mineralization and calcium homeostasis. Vitamin D deficiency causesboth musculoskeletal manifestations, including rickets, and extra-musculoskeletal symptoms. Because vitamin D is naturally present in only some foods, intake of daily foods cannot meet the dietary reference intake for vitamin D. Sunlight is the main source of vitamin D in humans therefore, the lack of sunlight can easily cause vitamin D deficiency in children and adolescents. Vitamin D deficiency can be diagnosed on the basis ofits typical clinical manifestation, laboratory tests, and radiologic findings. Detection of vitamin D deficiency in children or adolescents necessitates the simultaneous administration of vitamin D and calcium supplements. To prevent vitamin D deficiency, 200 IU of daily vitamin D intake is recommended in infants, and 400 IU of daily vitamin D intake is recommended in Korean children and adolescents.
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KEYWORD
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Vitamin D, Rickets, Deficiency, Children, Adolescents
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