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KMID : 1134220070270040023
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Hanyang Medical Reviews
2007 Volume.27 No. 4 p.23 ~ p.27
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The Use of PET in Esophageal Cancer
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Choi Joon-Young
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Abstract
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Esophageal cancer is one of the gastrointestinal malignancies that have an unfavorable prognosis. Whole body positron emission tomography (PET) using F-18 Fluorodeoxyglucose (FDG) has been used for characterizing focal lesions, initial staging, monitoring recurrence, and post-therapeutic follow-up in various malignant tumors. In esophageal cancer, FDG PET is not used for characterizing esophageal focal lesion. Due to better results for initial staging of esophageal cancer than chest CT or endoscopic ultrasound, especially in N and M staging, FDG PET provides valuable information for assessing prognosis and for selecting appropriate treatment. Although several studies are reported, FDG PET may be useful for restaging and detection of recurrence in esophageal cancer. For predicting pathological response to neoadjuvant therapy, FDG PET has been showed good results. Like other malignancies, integrated PET/CT is preferable to conventional PET in esophageal cancer considering better anatomical localization of hypermetabolic lesions and accuracy.
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KEYWORD
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Esophagus, Cancer, Positron emission tomography, PET/CT, 18F-fluorodeoxyglucose
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