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KMID : 1134220070270040059
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Hanyang Medical Reviews
2007 Volume.27 No. 4 p.59 ~ p.65
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PET Imaging for Gynecologic Malignancy
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Won Kyoung-Sook
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Abstract
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The utility of positron emission tomography (PET) in gynecologic malignancy has increased rapidly in recent years. This review examines publications in this area. PET scans in gynecologic malignancy are mostly performed using F-18 FDG. It is valuable in primary staging of untreated advanced cervical cancer, for post-treatment unexplained tumor marker elevation, and restaging of potentially curable recurrent cervical cancer. However, its value in early-stage cervical cancer
is limited. In ovarian cancer, sequential imaging predicts response to neoadjuvant chemotherapy and survival. It is also very useful when increases in CA 125 or CT/MRI defined recurrence is noted, but biopsy deemed infeasible. The role
of PET or PET/CT has evolved from a diagnostic tool into a potential indicator of response to treatment and prognosis. Evaluating PET or PET/CT using clinical impact is an attractive new endpoint.
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KEYWORD
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18-fluorodeoxyglucose, gynecologic malignancy, positron emission tomography, positron emission
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