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KMID : 1140120110160010051
Cancer Prevention Research
2011 Volume.16 No. 1 p.51 ~ p.57
Effects of Sea Tangle Supplementation and Exercise Training on the Antioxidant System Following Exhaustive Exercise Stress of the Rat
Kim Hyang-Suk

Kwak Yi-Sub
Kim Byung-Woo
Choi Yung-Hyun
Park Cheol
Hwang Hye-Jin
Abstract
This study was designed to investigate the effects of regular treadmill exercise and Sea Tangle (Laminaria japonica) supplementation on the antioxidant system following exercise stress. Treadmill exercise program were given to the 6-week-old rat by 10 miks/min for 30 minutes/day, and speed was elevated by 5 miks/min per week for 4 weeks. The experimental group was divided into 3: a control group (C), Sea Tangle supplement group (ST, Sea Tangle supplementation: 5 g/kg diet), and a group of treadmill £«Sea Tangle extract supplemented group (STT). After the treadmill exercise, these groups were further divided into those that had received the exercise stress for 1 hour (25 m/min) and those that had not experienced exercise stress. The activities of the superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase and malondialdehyde (MDA) concentrations were measured. There was a lower body weight decrease in the STT groups than in the C and ST group (p£¼0.05). The calatase activity was increased in STT group compared C and ST group after exercise stress. The SOD activity level without exercise stress showed a trend of increasing order as C£¼ST£¼STT, with a significant difference (p£¼0.05). And, the SOD activity after exercise stress was significantly increased in the ST and STT group than in the C group, but there was no significant difference between the ST and STT group. There was no difference in serum MDA concentration among the experimental groups in those that had not experienced exercise stress. However, the STT group with exercise stress showed a serum MDA concentration level significantly lower than those of the C and ST group (p£¼0.05). As a result, regular treadmill exercise and Sea Tangle supplementation could be considered important in controlling the oxidative stress after exercise stress.
KEYWORD
Sea Tangle supplementation, Treadmill exercise, Exercise stress, Antioxidant system
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