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KMID : 1141920170330020074
Annals of Coloproctology
2017 Volume.33 No. 2 p.74 ~ p.77
Pulmonary Sarcoidosis That Developed During the Treatment of a Patient With Crohn Disease by Using Infliximab
Kim Tae-Kyun

Kang Sun-Hyung
Moon Hee-Seok
Sung Jae-Kyu
Jeong Hyun-Yong
Eun Hyuk-Soo
Abstract
For inflammatory bowel disease (IBD), antitumor necrosis factor treatment offers a new direction for both patients and medical doctors. This treatment has dramatically improved the quality of life for patients with ulcerative colitis and Crohn disease (CD). However, with increasing usage and longer follow-up periods, a wider range of possible adverse effects may be encountered. We report an unusual case of pulmonary sarcoidosis developed during the treatment of a patient with CD by using infliximab. A 30-year-old male who had been treated for CD with infliximab for 18 months was admitted due to abnormal opacities on chest radiography. Chest computed tomography displayed clustered small nodules in both lobes and enlarged multiple lymph nodes. The patient was diagnosed with sarcoidosis from the results of a biopsy of the subcarinal lymph node. Lung lesions were improved five months after infliximab was stopped.
KEYWORD
Crohn disease, Tumor necrosis factor-alpha, Sarcoidosis, Adverse event
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