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KMID : 1142720220250020053
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Annals of Clinical Microbiology
2022 Volume.25 No. 2 p.53 ~ p.58
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Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections
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Kim Young-Ah
Kim Hee-Jung
Kim Do-Kyun
Liu Chang-Seung
Jeong Seok-Hoon
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Abstract
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Background: The incidence of community-associated (CA) Clostridioides difficile infection (CDI) has increased in Korea. In this study, we evaluated CA-CDI risk factors in terms of clinical features and ribotype considering its region-specific molecular epidemiology.
Methods: A retrospective case-control study was performed on two groups of CDI patients: 127 subjects with CA-CDI and 265 subjects with healthcare-associated (HA)-CDI. Risk factors for CA-CDI were evaluated in terms of clinical and microbiological features such as toxin type and ribotype.
Results: A comparison of the two groups of CDI patients revealed that inflammatory bowel disease, diarrhea, abdominal pain, and fever were more closely associated with CA-CDI. The toxin types and ribotypes of C. difficile were similar between the two groups. After adjusting for variables, no risk factors were identified for CA-CDI compared with HA-CDI.
Conclusion: Specific risk factors for CA-CDI were not identified in this study.
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KEYWORD
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Clostridioides difficile infection, Community-associated, Risk factor
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