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KMID : 1143420180110060152
Public Health Weekly Report
2018 Volume.11 No. 6 p.152 ~ p.158
Tuberculosis incidence and latent tuberculosis infection prevalence in high schools in Korea
Cho Kyung-Sook

Abstract
Objectives: The purpose of this study was to investigate tuberculosis (TB) incidence and latent TB infection (LTBI) prevalence among high school students in Korea.

Methods: With the concerned literature review, data were retrieved from notified new TB cases through the Integrated Disease and Health Control System from the year 2010-2016, and from contact investigations and screening for LTBI during 2012-2017.

Results: In the Republic of Korea, the notification rate of new TB cases among individuals aged 16-18 years markedly decreased from 62.5 per 100,000 population in 2010 to 23.5 per 100,000 population in 2016(an annual decrease rate of 10.6%), whereas that among all age groups decreased from 72.8 per 100,000 population in 2010 to 60.4 per 100,000 population in 2016(an annual decrease rate of 2.8%). Furthermore, the fraction of TB cases among 16-18-year-old individuals declined from 3.8% (1,382 cases) in 2010 to 1.5% (449 cases) in 2016. In the targeted contact investigations, the prevalence of LTBI among high school students ranged from 2.1% to 5.9%, with a mean rate of 4.8% during 2013-2016 (6.8% at a high school in 2016: 30% among close contacts and 4.6% among casual contacts), whereas the positivity rates in the LTBI screening program for general high school population ranged from 1.2% to 2.1% during 2014-2017.

Conclusions: These findings demonstrate that LTBI screening and treatment based on contact investigation, especially for close contacts, in schools should be prioritized in national TB control program.
KEYWORD
Tuberculosis, Tuberculosis incidence, Latent tuberculosis infection, Contact investigation, High school, Latent tuberculosis infection screening
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