KMID : 1143720080040020057
|
|
Korean Journal of Neurotrauma 2008 Volume.4 No. 2 p.57 ~ p.61
|
|
The Significance of Pupillary Light Reflex of Patient in Barbiturate Coma Therapy
|
|
Cho Pyung-Goo
Whang Kum Pyen Jhin-Soo Hu Chul Hong Soon-Ki Jung Hyun-Ho
|
|
Abstract
|
|
|
Objective:The aim of this study was to examine the significance of pupillary light reflex (PLR) during barbiturate coma therapy (BCT) against severe brain swelling.
Methods:Between January 2003 and October 2007, 28 patients (traumatic brain injury: 15) underwent BCT because of maintained severe brain swelling after operation. All the patients maintained 3-6th wave per minute activity on electro-encephalography, and PLR were checked every 2 hours during BCT. The patient¡¯s performance was checked using Glasgow outcome scale (GOS) at the average 19.6 days (1-60 days) after BCT.
Results:Twenty one patients had PLR at the start of BCT. Among 21 patients, 12 patient¡¯s PLR were vanished during BCT. Nine of 12 patients were dead (GOS=1), two had severe disability (GOS=2), and one stayed persistent vegetative state (GOS =3). But other nine patient¡¯s group, who showed prompt PLR continuously during BCT, got more improved GOS, compared with PLR vanished patient¡¯s group; 7 of 9 patients ranked more than GOS score 3.
Conclusion:Our clinical data suggest that the maintaining prompt PLR during BCT is a positive finding to predict good outcome.
|
|
KEYWORD
|
|
Barbiturate coma therapy, Pupillary light reflex, Severe brain swelling
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|