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KMID : 1143720130090020120
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Korean Journal of Neurotrauma
2013 Volume.9 No. 2 p.120 ~ p.124
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Risk Factors for Subsequent Fracture after Osteoporotic Vertebral Compression Fracture
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Kim Sung-Gon
Yang Joo-Chul
Kim Tae-Wan
Park Kwan-Ho
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Abstract
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ObjectivesPercutaneous vertebroplasty is an effective treatment that relieves pain caused by vertebral compression fracture. However, vertebroplasty may increase the risk for subsequent vertebral compression fracture. The purpose of this study is to evaluate the incidence of and risk factors for subsequent fracture after vertebroplasty.
Methods: A retrospective analysis was performed for 112 patients who were diagnosed with a first osteoporotic compression fracture at a single level and underwent vertebroplasty at that level. Possible risk factors for subsequent fracture, such as age, sex, bone mineral density (BMD), location of treated vertebrae, pattern of cement distribution, cement volume, presence of intradiscal cement leakage, and direction of cement leakage, were analyzed.
Results:During the follow-up period, 18 new subsequent vertebral fractures developed (16.1%). Subsequent fractures were more common in osteoporotic patients (T-score ≤-2.5)(p=0.034, r=0.208). Intravertebral cement volume ≥3.5 cc were also associated with a significantly higher risk of fracture (p=0.012, r=0.238).
Conclusion:Low BMD and volume of intravertebral cement were the factors most strongly associated with subsequent fracture after percutaneous vertebroplasty.
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KEYWORD
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Osteoporotic compression fracture, Bone mineral density, Cement volume
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