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KMID : 1147220230240030101
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Journal of Biomedical and Translational Research
2023 Volume.24 No. 3 p.101 ~ p.104
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Unusual case of multifocal cerebral infarction in a patient with gastric mucosa-associated lymphoid tissue lymphoma
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Chae Hee-Yun
Han Jeung-Wan
Yum Kyu-Sun
Lee Sung-Hyun
Lee Sang-Soo
Kim Jin-Hyun
Han Ho-Seong
Shin Dong-Ick
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Abstract
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Mucosa-associated lymphoid tissue (MALT) lymphoma (ML) is a type of non-Hodgkin’s lymphoma involving MALT, commonly the stomach or salivary glands, although virtually any mucosal site can be affected. ML originates from B cells in the marginal zone of MALT, and is also called extranodal marginal zone B cell lymphoma. It is a slow-growing cancer that usually responds well to treatment. A 59-year-old female presented with a 1-day history of quadriparesis and dysarthria. Up arrival at the hospital, motor power in the right upper and lower extremities was grade 3/5 according to the Medical Research Council scale, while that in the left leg was 4/5. The patient had been diagnosed with gastric ML 1 year prior, and had received antibiotics during the previous 2 weeks. The emergency magnetic resonance imaging of the brain performed at the time of presentation showed multifocal embolic infarction in the cerebral hemisphere bilaterally, which did not have a cardiac origin. Magnetic resonance angiography revealed no stenotic or occlusive lesions. Secondary prophylaxis with daily administration of 300 mg aspirin was prescribed. The patient was discharged with residual right hemiparesis 2 weeks after the onset of symptoms. Herein, we present a rare case of multifocal cerebral infarction in a gastric ML patient.
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KEYWORD
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multifocal infarction, lymphoma, B-cell, marginal zone, embolic infarction, cancer, aspirin
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