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KMID : 1148920120460020095
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Nuclear Medicine and Molecular Imaging
2012 Volume.46 No. 2 p.95 ~ p.101
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Diagnostic Criteria on 18F-FDG PET/CT for Differentiating Benign from Malignant Focal Hypermetabolic Lesions of Parotid Gland
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Park Soo-Bin
Choi Joon-Young
Lee Eun-Jeong
Yoo Jang
Cheon Mi-Ju
Cho Suk-Kyong
Choe Yearn-Seong
Lee Kyung-Han
Kim Byung-Tae
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Abstract
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Purpose: We investigated PET/CT diagnostic criteria for differentiating benign from malignant parotid lesions with focal 18F-FDG uptake.
Methods: The subjects of the study were 272 patients who exhibited focal 18F-FDG uptake of the parotid gland. Sixty-eight pathologically confirmed parotid lesions from 67 patients were included. The maximum SUV (SUVmax), uptake patterns (homogeneous vs. heterogeneous), size measured by CT, maximum Hounsfield units (HUmax) and margins on CT (well vs. ill defined) of each parotid lesion on PET/CT images were compared with final diagnoses.
Results: Thirty-two parotid lesions were histologically proven to be malignant. There were significant differences in uptake patterns (cancer incidence, heterogeneous:homogeneous?=?79.2%:29.5%, p?
Conclusion: Uptake patterns and margins on CT are useful PET/CT diagnostic criteria for differentiating benign from malignant lesions.
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KEYWORD
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F-FDG, PET, PET/CT, Parotid gland, Cancer
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