KMID : 1148920120460020129
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Nuclear Medicine and Molecular Imaging 2012 Volume.46 No. 2 p.129 ~ p.133
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Ga-68 Somatostatin Receptor PET/CT in von Hippel-Lindau Disease
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Oh Jong-Ryool
Kulkarni Harshad Carreras Cecilia Schalch Georg Min Jung-Joon Baum Richard P.
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Abstract
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Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer syndrome with a variety of benign and malignant tumors such as retinal and central nervous system hemangioblastomas, endolymphatic sac tumors, renal cysts and tumors, pancreatic cysts and tumors, pheochromocytomas, and epididymal cystadenomas. Cross-sectional modalities (computed tomography and magnetic resonance imaging) as well as ultrasound play a major role in the initial evaluation and follow-up of the various manifestations of VHL disease. Ga-68-labeled somatostatin receptor analogs already have a significant role in the diagnosis, staging, and therapy management of neuroendocrine neoplasms and neural crest tumors. Herein, we report a case presenting a variety of malignancies in VHL and showing the usefulness of Ga-68 somatostatin receptor PET/CT as a one-stop-shop imaging modality in the management of VHL disease.
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KEYWORD
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Ga-68 DOTA-TOC PET/CT, Ga-68 DOTA-TATE PET/CT, Ga-68 DOTA-NOC PET/CT von Hippel-Lindau disease, Hemangioblastoma, Pheochromocytoma
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