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KMID : 1148920120460030196
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Nuclear Medicine and Molecular Imaging
2012 Volume.46 No. 3 p.196 ~ p.200
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Dual-time-point FDG PET/CT: Is It Useful for Lymph Node Staging in Patients with Non-Small-Cell Lung Cancer?
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Kim Dae-Weung
Kim Woo-Hyoung
Kim Chang-Guhn
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Abstract
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Purpose: Dual-time-point (DTP) FDG PET/CT has been shown to be useful for lymph node (LN) staging in patients with non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the LN staging ability of DTP FDG PET/CT in the predominant area of pulmonary tuberculosis.
Methods: Sixty-nine NSCLC patients underwent DTP PET/CT. Regions of interest were placed on each LN of each station, and the maximum SUVs were measured. Three variables were obtained: (1) the SUV on the early scan (SUVearly), (2) the SUV on the delayed scan (SUVdelayed), and (3) the retention index of the SUV (RI). Each patient had one final LN stage and three other LN stages according to the cutoff values of SUVearly, SUVdelayed, and RI.
Results: In the LN-based analysis, the area under the ROC curve of SUVdelayed (0.884) was significantly larger (P?
Conclusions: In this study, comparing the diagnostic efficacy of SUVearly, SUVdelayed, and RI for LN staging in patients with NSCLC, SUVdelayed was the most accurate variable for LN staging. DTP PET/CT could provide improved diagnostic accuracy for the LN staging of NSCLC.
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KEYWORD
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Non-small-cell lung cancer, Fluorodeoxyglucose, Positron emission tomography, Dual-time-point imaging, Lymph node staging
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