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KMID : 1148920120460040261
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Nuclear Medicine and Molecular Imaging
2012 Volume.46 No. 4 p.261 ~ p.268
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Detectability of T-Measurable Diseases in Advanced Gastric Cancer on FDG PET-CT
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Oh Sun-Young
Cheon Gi-Jeong
Kim Young-Chul
Jeong Eu-Gene
Kim Seung-Eun
Choe Jae-Gol
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Abstract
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Purpose: Usefulness of FDG PET-CT in monitoring response in locally advanced gastric cancer has been reported. The purpose of this study was to evaluate the related factors to detect measurable diseases in advanced gastric cancer on FDG PET-CT.
Methods: We retrospectively reviewed 38 patients diagnosed as having advanced gastric cancer. We defined the measurable diseases when there was visualized tumor of which maximum standardized uptake value (SUVmax) was higher than 1.35*SUVmax of liver + 2*SD of liver SUV. We evaluated what kinds of factors from the clinicopathologic features were related to identifying measurable diseases.
Results: Of 38 patients with advanced gastric cancer, 18 (50 %) had measurable tumors on FDG PET-CT. Measurable tumors were significantly more frequent in well or moderately differentiated adenocarcinoma (70.5 % vs 35.3 %, p?
Conclusion: We found that age at diagnosis, as well as histologic types and location of tumors, were the affecting factors to detect measurable disease on FDG PET-CT in patients with advanced gastric cancer. Our study suggests that elderly patients of age of 55 years old or more can frequently have T-measurable disease on FDG PET-CT in advanced gastric cancer and FDG PET-CT will be helpful to monitor measurable disease.
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KEYWORD
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Advanced gastric cancer, Measurable disease, FDG PET-CT, Age at diagnosis, Affecting factor
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