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KMID : 1148920130470030208
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Nuclear Medicine and Molecular Imaging
2013 Volume.47 No. 3 p.208 ~ p.211
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Diffuse Myocardial Uptake of 99mTc-HDP in Multiple Myeloma
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Demirel Koray
Sadic Murat
Korkmaz Meliha
Comak Aylin
Atilgan Hasan Ikbal
Koca Gokhan
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Abstract
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Soft tissue uptake is a rare finding in bone scintigraphy, with an incidence of 2%. Although the mechanism has not yet been fully clarified, several causes have been reported for this unusual uptake pattern. This paper presents a case of diffuse myocardial accumulation of technetium-99m hydroxymethylene diphosphonate (99mTc-HDP) without either solid/visceral organ or soft tissue with multiple myeloma (MM) in skeletal scintigraphy. A 93-year-old man with hypertension and chronic heart failure for 14 years underwent bone scanning due to a 2-month history of back pain within a 1-year period of MM. Three hours later, 99mTc-HDP late static images showed diffuse myocardial radiotracer accumulation and there were no other sites of abnormal soft tissue or visceral uptake. Myocardial accumulation had disappeared on 24-h delayed static images. This accumulation was thought to be related with AL-type amyloidosis associated with MM.
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KEYWORD
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Technetium-99m hydroxymethylene diphosphonate (99mTc-HDP), Technetium-99m bone agents, Myocardial uptake, Multiple myeloma
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