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KMID : 1148920140480010072
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Nuclear Medicine and Molecular Imaging
2014 Volume.48 No. 1 p.72 ~ p.74
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Impact of Nonosseous Findings on 18F-NaF PET/CT in a Patient with Ductal Breast Carcinoma
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Kuyumcu Serkan
Adalet Isik
Isik Emine Goknur
Unal Seher Nilgun
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Abstract
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18F-NaF was used as a bone-seeking PET tracer for skeletal imaging until the introduction of the widely available 99mTc-labeled bone agents. However, there is renewed clinical interest in 18F-NaF since prior technical and logistic limitations to its routine use are no longer present, and, as a consequence, it is likely that uptake unrelated to bone and non-osseous findings will be encountered more frequently. As a result of tumoral necrosis, soft tissue metastases may demonstrate 18F-NaF avidity due to dystrophic calcification. On the other hand, all non-osseous findings, whether 18F-NaF avid or not, may provide important diagnostic information that may alter the course of the disease, including treatment options. Herein we present a patient with ductal carcinoma of the breast in whom findings unrelated to the skeletal system in 18F-NaF PET/CT altered the treatment strategy.
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KEYWORD
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18F-NaF PET/CT, 18F-FDG PET/CT, Bone metastasis, Breast carcinoma
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