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KMID : 1148920140480040303
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Nuclear Medicine and Molecular Imaging
2014 Volume.48 No. 4 p.303 ~ p.305
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Brain MRI, Tc-99m HMPAO SPECT and F-18 FP-CIT PET/CT Findings in a Patient with Wilson Disease: A Case Report
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Kim Seung-Yoo
Song In-Uk
Chung Yong-An
Choi Eun-Kyung
Oh Jin-Kyoung
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Abstract
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A 34-year-old female had experienced head and hand tremors with a dystonic component for 8 months. Brain MRI showed T2 high signal intensity in the periaqueductal region, dorsal midbrain and dorsal upper pons. No abnormal uptake was noted on Tc-99m HMPAO SPECT or F-18 FP-CIT PET/CT. Wilson disease was diagnosed according to the 2008 consensus guideline from the American Association for the Study of Liver Disease and 2012 guideline from the European Association for the Study of the Liver. This case demonstrates T2 signal change in the basal ganglia, excluding the putamen, in a Wilson disease patient with relatively severe clinical findings, but normal Tc-99m HMPAO SPECT and F-18 FP-CIT PET/CT.
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KEYWORD
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Wilson disease, MRI, Tc-99m HMPAO SPECT, F-18 FP-CIT PET/CT
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