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KMID : 1148920180520040247
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Nuclear Medicine and Molecular Imaging
2018 Volume.52 No. 4 p.247 ~ p.253
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Factors Associated with Dose Determination of Radioactive Iodine Therapy for Differentiated Thyroid Cancer
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Hong Chae-Moon
Ahn Byeong-Cheol
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Abstract
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Radioactive iodine (RAI) therapy for differentiated thyroid cancer has been successfully used for more than 70 years. However, there is still plenty of controversy surrounding the use and doses of radioiodine. There is insufficient evidence to answer the questions. Recent American Thyroid Association (ATA) guidelines seem to favor low-dose RAI, based on recent clinical trials and meta-analyses. However, long-term follow-up data remains limited, and there are additional factors we should consider that might affect the efficacy of RAI therapy. Therefore, until sufficient data are available, it is necessary to remain cautious about determining RAI doses by considering multiple patient-specific variables.
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KEYWORD
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Differentiated thyroid cancer, I-131, Radioactive iodine, High dose, Low dose
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