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KMID : 1156220200460030324
Journal of Environmental Health Sciences
2020 Volume.46 No. 3 p.324 ~ p.334
Monitoring of Biogenic Amines Content in Commercial Fermented Alcoholic Beverages in Gangwon-do and Risk Assessment
Bae Cheol-Min

Shin In-Cheol
Lee Woan
Lee Heok-Hwa
Choi Yeo-Eun
Kim Young-Ju
Lee Ga-Hee
Jeong Kyung-Jin
Choi Seung-Bong
Choi Seung-Bong
Abstract
Objectives: This study was conducted to estimate the related health risk by investigating the content of biogenic amines (BAs) in commercial fermented alcoholic beverages.

Methods: Ninety-seven samples, including takjus (34), fruit wines (26), distilled liquors (20) and beers (17) were purchased in Gangwon-do (Province) in 2019. The eight BAs (putrescine, cadaverine, spermine, spermidine, tyramine, ¥â-phenylethylamine, histamine, and tryptamine) were analyzed by high performance liquid chromatograph (HPLC) after extraction (0.4 M HClO4), pigment removal (carbon cartridge) and derivatization (1% dansylchloride). The health risk of exposure to BAs due to ingestion of commercial fermented alcoholic beverages was estimated as the margin of exposure (MOE).

Results: Various BAs were detected in takju, fruit wine, distilled liquor and beer. Putrescine (not detected (ND)- 12.60 mg/L), cadaverine (ND-5.45 mg/L), tyramine (ND-8.34 mg/L), ¥â-phenylethylamine (ND-13.73 mg/L), histamine (ND-7.96 mg/L), and tryptamine (ND-19.00 mg/L) were found in takju. Putrescine (ND-15.34 mg/L), cadaverine (ND-7.90 mg/L), ¥â-phenylethylamine (ND-3.06 mg/L), histamine (ND-9.68 mg/L), and tryptamine (ND-14.06 mg/L) were identified in fruit wine. Putrescine (less than limit of detection (
Conclusions: The commercial fermented alcoholic beverages contained various BAs, and there was a difference in BA species and detection amount according to type. The health risk was estimated to be low given that the MOE was all greater than ten.
KEYWORD
Biogenic amines, fermented alcoholic beverages, risk assessment, margin of exposure
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