|
KMID : 1157520100060020089
|
|
International Journal of Clinical Preventive Dentistry
2010 Volume.6 No. 2 p.89 ~ p.98
|
|
|
Improving Effect on Oral Conditions with Dentifrice Combined by Extracts of Dipotassium Glycyrrhizinate, Bamboo Salt and Quantitative Extracts of Centella Asiatica
|
|
Park Yong-Duk
Nam Dong-Wang
Seong Jeong-Min
Hwang Ji-Min
Kim Ji-Hyun
Lee Sun-Kyoung
Ahn Kwang-Sik
Yoo Su-Min
Cho Ja-Won
Moon Kyo-Tae
Lee Seol-Hoon
Ahn Jae-Hyun
|
|
|
Abstract
|
|
|
Objective: This experiment was contrived to find out the changed in oral condition index when standardized and regular use of the dentifrice is done according to the usage of dosage of the dentifrice.
Methods: After inspecting the result of acceleration of collagen forming and suppressing effect of inflammatory reaction by using the titrated extracts of Centella asiatica and Dipotassium glycyrrhizinate with In-vitro experiment (done inside the lab), the remedying effect on oral cavity condition was to be obtained with dentifrice made with combined bamboo salt and those above through in-vivo experiment (clinical) worked with 90 healthy bodied examinees for over 6 months.
Results: With the result of the experiment done at the lab, when the changes of improved index of oral cavity condition, MMP-1 formative inhibition analysis, and collagen analysis were obtained during the experiment periods, the titrated extract of Centella asiatica suppresses the damage of the tissue due to inflammatory response at the gingiva cell and after the inflammatory response, accelerated regeneration of the gingiva were clearly shown. Also, as with the result in clinical experiment, the effect was acceptable in reducing effect of dental plaque index and gingivitis index with dentifrice that only contains the titrated extract of Centella asiatica and also showed outstanding result in antibacterial activity.
Conclusion: The most effective improvement especially shown on the oral conditions were dentifrice that contains Dipotassium glycyrrhizinate, bamboo salt and titrated extracts of Centella asiatica.
|
|
|
KEYWORD
|
|
|
bamboo salt, centella asiatica, dipotassium glycyrrhizinate, toothpaste
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
|