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KMID : 1161420200230030206
Journal of Medicinal Food
2020 Volume.23 No. 3 p.206 ~ p.214
Biochemical, Anthropometric, and Physiological Responses to Carbohydrate-Restricted Diets Versus a Low-Fat Diet in Obese Adults: A Randomized Crossover Trial
Petrisko Mayumi

Kloss Rebecca
Bradley Patricia
Birrenkott Erika
Spindler Audrey
Clayton Zachary S.
Kern Mark
Abstract
Some research supports high-fat carbohydrate (CHO)-restricted diets for weight and fat loss and improvement of cardiovascular disease risk factors. To test this, a randomized crossover study was designed. Subjects (17 obese men and women [BMI: 30?38?kg/m2]) were fed three diets (supplying 1600 and 2200 kilocalories (kcal)/day for women and men, respectively) for 4 weeks, with each trial separated by 4-week washout periods. One CHO-restricted diet (10% CHO, 50% fat, and 40% protein content) was rich in plant foods and mushrooms, while the other CHO-restricted diet included more animal foods (10% CHO, 60% fat, and 30% protein content). The third diet was lower in fat and protein content (LF) and higher in CHOs (61% CHO, 21% fat, and 18% protein content). Body composition was assessed through hydrostatic weighing before and after each diet trial. Fasting blood samples were collected weekly for analysis of hormones and lipids. Data were analyzed through repeated measures analysis of variance with post hoc paired comparison t-tests. Weight and fat loss were similar (P?>?.05) among trials. Subjects lost lean mass (P?
KEYWORD
animal protein, carbohydrate restriction, high fat diet, low fat diet, mushrooms, plant protein
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