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KMID : 1161820210060010001
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Journal of Natural Healing
2021 Volume.6 No. 1 p.1 ~ p.7
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Anti-oxidant and Anti-inflammatory effects of Usnea diffracta Vain. extracts
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Choi Yeon
Kim Jong-Du
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Abstract
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This study investigated antioxidant and anti-inflammatory in order to confirm the possibility of functional materials that can improve skin diseases using Usnea diffracta Vain. extracts. As a result of measuring DPPH and ABTS free radical scavenging activities, it was confirmed that 50%% ethanol, 70% ethanol, and 95% ethanol extracts had superior antioxidant activity compared to other solvent extracts. In particular, in the case of 70% ethanol, 95% ethanol extract, it was confirmed that the antioxidant ability was excellent even at a low concentration compared to other extracts. As a result of confirming the efficacy of reducing skin inflammation against 70% ethanol, 95% ethanol extract using the HaCaT cell line, it was confirmed that the protein level of the CCL17 and CCL22 cytokine increased by TNF-α and IFN-γ decreased dosedependent, respectively. In conclusion, the 70% ethanol, 95% ethanol extract of Usnea diffracta Vain. is likely to be used as a functional material related to skin diseases in the future.
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KEYWORD
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Usnea diffracta Vain., anti-oxidant, anti-inflammatory, cytokine, skin diseases
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