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KMID : 1164620200530010001
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Korean Journal of Thoracic and Cardiovascular Surgery
2020 Volume.53 No. 1 p.1 ~ p.7
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Surgical Outcomes for Native Valve Endocarditis
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Park Bong-Suk
Lee Won-Yong
Ra Yong-Joon
Lee Hong-Kyu
Gu Byung-Mo
Yang Jun-Tae
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Abstract
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Background: The aim of this study was to evaluate the short-term and long-term results of surgical treatment for native valve endocarditis (NVE) and to investigate the risk factors associated with mortality.
Methods: Data including patients’ characteristics, operative findings, postoperative results, and survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital.
Results: A total of 29 patients underwent surgery for NVE (affecting the mitral valve in 20 patients and the aortic valve in 9) between 2003 and 2017. During the follow-up period (median, 46.9 months; interquartile range, 19.1?107.0 months), the 5-year survival rate was 77.2%. In logistic regression analysis, body mass index (p=0.031; odds ratio [OR], 0.574; 95% confidence interval [CI], 0.346?0.951), end-stage renal disease (ESRD) (p=0.026; OR, 24.0; 95% CI, 1.459?394.8), and urgent surgery (p=0.010; OR, 34.5; 95% CI, 2.353?505.7) were significantly associated with in-hospital mortality. Based on Cox proportional hazard regression analysis, the statistically significant predictors of long-term outcomes were hypertension, ESRD, and urgent surgery.
Conclusion: Surgical treatment for NVE is associated with considerable mortality. The in-hospital mortality and 5-year survival rates of this study were 13.8% and 77.2%, respectively. Underlying conditions, including hypertension and ESRD, and urgent surgery were independent risk factors for unfavorable outcomes.
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KEYWORD
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Endocarditis, Surgery, Outcomes, Heart valve disease, Risk factors
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