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KMID : 1164620200530060381
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Korean Journal of Thoracic and Cardiovascular Surgery
2020 Volume.53 No. 6 p.381 ~ p.386
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Characterization of Venous Involvement in Vasculo-Behcet Disease
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Lee Na-Hyeon
Bae Mi-Ju
Jin Mo-Ran
Chung Sung-Woon
Lee Chung-Won
Jeon Chang-Ho
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Abstract
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Background: Behcet disease is a chronic inflammatory disorder with a varying etiology. Herein, we report the involvement of peripheral veins in Behcet disease and discuss the treatment thereof.
Methods: Thirty-four patients with venous involvement in vasculo-Behcet disease were retrospectively analyzed over 15 years. We reviewed the clinical manifestations, treatment choices, and complications of these patients.
Results: Deep vein thrombosis (DVT) was observed in 24 patients (70.59%) and varicose veins in 19 (52.94%). Immunosuppressive treatment was administered to all patients due to the pathological feature of vein wall inflammation. In patients with DVT, anticoagulation therapy was also used, but post-thrombotic syndrome was observed in all patients along with chronic luminal changes. Eleven patients with isolated varicose veins underwent surgery; although symptoms and lesions recurred in half of these patients, no cases of secondary DVT occurred.
Conclusion: When DVT was diagnosed in patients with Behcet disease, there was no cure for the lesions. Ultrasonographic abnormalities were observed in all patients, and post-thrombotic syndrome remained to varying degrees. In cases of isolated varicose veins in patients with Behcet disease, DVT did not occur after surgical treatment. If the activity of Behcet disease is controlled, surgical correction of varicose veins is preferable.
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KEYWORD
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Behcet syndrome, Venous thrombosis, Thrombophlebitis
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