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KMID : 1164620210540050396
Korean Journal of Thoracic and Cardiovascular Surgery
2021 Volume.54 No. 5 p.396 ~ p.399
Guillain-Barre Syndrome after Lung Transplantation in the Immediate Postoperative Period: Case Report
Gu Byung-Mo

Ko Ho-Hyun
Lee Hong-Kyu
Ra Yong-Joon
Lee Hee-Sung
Kim Hyoung-Soo
Abstract
A 58-year-old man, incapable of maintaining oxygen saturation with mechanical ventilation, was admitted to our hospital for veno-venous extracorporeal membrane oxygenation (ECMO) treatment. He was diagnosed with acute respiratory distress syndrome (ARDS) due to influenza A pneumonia. His condition stabilized with antibiotics and steroid administration, but weaning from ECMO failed due to post-infectious pulmonary sequelae. On day 84 after admission, he underwent bilateral lung transplantation. In the postoperative phase, he did not regain consciousness even after discontinuation of sedatives for 3 days. However, spontaneous pupillary reflex and eye movements were preserved, while communication and upper and lower limb movements were affected. The nerve conduction study was diagnostic of Guillain-Barre syndrome. He was managed with intravenous immunoglobulins and plasmapheresis. Mild recovery of the facial muscles was seen, but he died 24 days post-surgery due to progressive ARDS and sepsis.
KEYWORD
Guillain-Barre syndrome, Lung transplantation, Extracorporeal circulation, Complication, Acute respiratory distress syndrome, Case report
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