KMID : 1188320070010010033
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Gut and Liver 2007 Volume.1 No. 1 p.33 ~ p.39
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Features of Gastric Neoplasm Detected during the Screening Examination
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Park Min-Jeoung
Kim Dong-Hee Lim Seon-Hee Yim Jeong-Yoon Kim Young-Sun Choi Keong-Ran Jung Hyun-Chae Song In-Sung Kim Sun-Sin Yoon Dae-Hyun Shin Chan-Soo Cho Sang-Heon Oh Byung-Hee Lee Dong-Ho
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Abstract
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Background:Gastric cancer is the leading malignancy in Korea and early detection through the health screening seems to be important. The aims of this study were to investigate the features of gastric neoplasms detected during screening, and to figure out the risk factors of these lesions.
Method: From October 2003 to September 2005, subjects who visited Seoul National University Hospital Healthcare System Gangnam Center for health check-up were included in the study. The program included a questionnaire and tests including anti-Helicobacter pylori (H. pylori) antibody, esophagogastroduodenoscopy or double contrast upper gastrointestinal study. To figure out the risk factors, an age and gender-matched, four-fold sized control group was selected from the subjects.
Results: Of 25, 432 subjects, 122 cases of gastric neoplasms were detected including 61 adenocarcinoma (45 early gastric cancers), 53 adenoma, 7 mucosa-associated lymphoid tissue lymphoma, and one metastatic cancer. There was no significant statistical difference in basal characteristics of the subjects between gastric adenocarcinoma and adenoma. When comparing with the control group those without gastric neoplasms, smoking history, family history of stomach cancer, and H. pylori seropositivity were found to be significant risk factors for gastric neo-plasms. Metabolic syndrome was more prevalent in adenoma than in the control (p£¼0.05).
Conclusions: The health screening may be beneficial in early detection of gastric cancer. In addition, metabolic syndrome might be related with gastric adenoma.
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KEYWORD
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Gastric cancer, Screening, Stomach, Ade--noma, Risk factor, Helicobacter pylori
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