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KMID : 1188320110050010110
Gut and Liver
2011 Volume.5 No. 1 p.110 ~ p.114
Delayed Viral Clearance of Chronic Hepatitis C in Patients after Treatment Failure
Cho Su-Hyun

Lee Sung-Wook
Choi Seok-Reyol
Han Sang-Young
Roh Myung-Hwan
Lee Jong-Hoon
Jang Jin-Seok
Baek Yang-Hyun
Kim Su-Young
Abstract
Hepatitis C virus (HCV) infection usually progresses to chronic hepatitis, with rare cases of spontaneous viral eradication. We present herein four cases involving patients that were initially declared to have failed to respond to treatments, based on the presence of HCV RNA that was still detectable after completion of the standard treatment for chronic hepatitis C with genotype 2. However, the HCV RNA became undetectable, with a delayed response, after discontinuation of therapy. Two of the four patients were diagnosed as treatment failures after extended treatment, and the other two received no further treatment after the standard treatment. All four patients maintained a sustained virological response during the periodic follow-up after delayed viral clearance.
KEYWORD
Delayed viral clearance, Chronic hepatitis C, Sustained virological response
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