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KMID : 1189420050180010234
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2005 Volume.18 No. 1 p.234 ~ p.240
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The Study on the Anti-Allergic Rhinitis Effects of Gamigyejitang (focus on histological changes)
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Park Jin-Mee
Sim Sung-Yong
Byun Hak-Sung
Kim Kyung-Jun
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Abstract
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This study is for Gamigyejitang’s effects on the histological change s of allergic rhinitis. for this purpose, the changes of the mucosa epithelium and the submucosa tissue of nose were observed and the effects on neutrophil count and eosinophil count in blood were estimated. The rats were divided into normal group, control group and experimental group. Control group was administered normal saline and experimental group was administerd Gamigyejitang. The results obtained were as follows: 1. The epithelium layer of experimental group was restored to normal thickness and state nearly. 2. The submucosa tissue of experimental group was restored to normal state nearly. 3. The neutrophil count and eosinophil count were decreased in the experimental group(Gamigyejitang treated group) as compared with the control group but not significantly. According to above results, it is supposed that Gamigyejitang has considerable effect on allergic rhinitis and could be applicated to treat the nasal mucosa edema and several symptoms.
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KEYWORD
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Allergicrhinitis, Gamigyejitang, Neutrophilcount, Eosinophilcount, Epitheliumlayer, Submucosatissue
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