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KMID : 1189420050180020028
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2005 Volume.18 No. 2 p.28 ~ p.35
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The Effects of Gudambopae-Tang on Changes of Cytokines in Allergic Rhinitis Model
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Yang Hee-Yeon
Kim Yoon-Bum
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Abstract
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In order to investigate the effects of Gudambopae-Tang on allergic rhinitis, laboratory study about cytokines and OVA-specific IgE was perfomed in the present study. The results are summarized as follow; 1. IL4, IL-5 was increased in medicating group than control group. 2. IFN-r was increased in medicating group than control group. 3. total IgE and OVA-specific IgE was significant decreased in medicating group than control group, statistically significant. This study shows experimentally that Gudambopae-tang could reduce allergic reaction in allergic rhinitis. Advanced studies are required to investigate the mechanisms of herbal medicine in allergic rhinitis model.
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KEYWORD
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allergicrhinitis, Gudambopae-tang, IL4, IL-5, IFN-r, totalIgEandOVA-specificIgE
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