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KMID : 1200820190190030251
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Oriental Pharmacy and Experimental Medicine
2019 Volume.19 No. 3 p.251 ~ p.258
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New aliphatic ester constituents of Hygrophila auriculata (K. Schum) Heine from the Koshi river basin
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Hussain Md. Sarfaraj
Gebira Hesham Mustafa
Ismail Hend
Ali Mohammed
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Abstract
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This research is meant for the isolation of the compounds out from the methanolic extract of the Hygrophila auriculata. This herb was customarily used as a diuretic to cure the inflammation, pain, urinal infections, and the gout. To isolate the compounds from methanolic extract of Hygrophila auriculata which was taken from Bihar’s Koshi river belt, open silica gel column chromatographic methods with different solvent mixtures were applied. The elucidation of the structure of the different separated phytoconstituent was accomplished through spectral data analysis, chemical reactions and their literary comparisons. Phytochemical analysis of methanolic extract of Hygrophila auriculata gave a new compound identified as n-octa-triacontan-3-one-19α, 31α-diol (4) and along with the four known aliphatic ester compounds n-hexacos-21-one-1-ol (1), trans-tetracont-7-en-1-ol (2), n?octacosan-8-one (3) and n-heptacosan-11α-ol (5). A new compound was found with four other known compounds as aliphatic esters from H. auriculata extract.
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KEYWORD
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Hygrophila auriculata, Methanolic extract, Phytochemical investigation, Aliphatic esters
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