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KMID : 1200820200200040673
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Oriental Pharmacy and Experimental Medicine
2020 Volume.20 No. 4 p.673 ~ p.679
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Chemical composition, antibacterial and antifungal activities of Thymus leptobotrys Murb essential oil
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Oubihi Asmaa
Ouryemchi Imane
Nounah Issmail
Tarfaoui Kelthoum
Harhar Hicham
Ouhssine Mohammed
Guessous Zineb
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Abstract
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The objective of this work is to study the chemical composition of Thymus leptobotrys Murb essential oil and its antimicrobial properties on ten bacteria and three yeasts. The essential oil is extracted by hydrodistillation and analyzed by gas chromatography coupled with mass spectrometry (GC/MS). The active substances are monoterpenic alcohols, mainly carvacrol (73.68%), and monoterpenic hydrocarbons: p-cymene (8.68%) and γ-terpinene (4.14%). The antibacterial and antifungal activity determined by disc diffusion method reveals an inhibitory effect of the essential oil on all studied strains, the potential for inhibition being greater than the reference antibiotics (Ciprofloxacin and Amoxicillin).
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KEYWORD
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Thymus leptobotrys Murb, Essential oil, Chemical composition, Antimicrobial activity, Antifungal activity
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