KMID : 1202320140070010010
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Brain & NeuroRehabilitation 2014 Volume.7 No. 1 p.10 ~ p.15
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Common Complications after Hypoxic-ischemic Encephalopathy
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Lim Seong-Hoon
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Abstract
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Hypoxic-ischemic encephalopathy (HIE) is one of the major disease for neuro-rehabilitation, as well asone of the important impairment. HIE typically shows global deterioration of brain function with relativepreservation of brain stem reflexes, and topographic pattern of damage; the CA1 hippocampal cells,cerebellar Purkinje cells, neocortical neurons in layers 3, 5, 6 and basal ganglia. The characteristics ofpatho-mechanism including persistent vegetative state, seizure, autonomic dysfunction and secondaryParkinsonism are causative factors of several complications. Management of these complications sometimescurative, but more often re-adaptive and palliative. Understanding and proper rehabilitation of complicationswill be one of the most important therapeutic strategies for patients with HIE.
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KEYWORD
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autonomic dysfunction, hypoxic-ischemic encephalopathy, persistent vegetative state, seizure, secondary parkinsonism
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