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KMID : 1204320200360010033
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Laboratory Animal Research
2020 Volume.36 No. 1 p.33 ~ p.33
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Cryopreservation of mouse resources
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Takeo Toru
Nakao Satohiro
Nakagawa Yoshiko
Sztein Jorge M.
Nakagata Naomi
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Abstract
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The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived in mouse banks worldwide. Researchers can request for the archived mouse strains for their research projects. The research infrastructure of mouse banks improves the availability of mouse resources, the productivity of research projects, and the reproducibility of animal experiments. Our research team manages the mouse bank at the Center for Animal Resources and Development in Kumamoto University and continuously develops new techniques in mouse reproductive technology to efficiently improve the system of mouse banking. In this review, we introduce the activities of mouse banks and the latest techniques used in mouse reproductive technology.
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KEYWORD
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Genetically engineered mice, Mouse bank, Reproductive technology, Sperm, Embryo, Cryopreservation, In vitro fertilization, Cold storage, Hands-on workshop
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