Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 1237720120450030170
Anatomy & Cell Biology
2012 Volume.45 No. 3 p.170 ~ p.177
Aloe vera gel and thyroid hormone cream may improve wound healing in Wistar rats
Tarameshloo Mahsa

Norouzian Mohsen
Zarein Dolab Saeed
Dadpay Masoomeh
Mohsenifar Jaleh
Gazor Roohollah
Abstract
Therapeutic effects of various treatment options in wound healing have been one of the most controversial issues in surgical science. The present study was carried out to examine and compare the effects of Aloe vera gel, thyroid hormone cream and silver sulfadiazine cream onsutured incisions in Wistar rats. In a randomized controlled trial, thirty-six Wistar male rats, 250 to 300 g, received surgical incisions followed by topical application of Aloe vera gel, thyroid hormone cream and silver sulfadiazine 1%. To assess the efficacy of each treatment technique, a histological approach was used to evaluate the mean number of fibroblasts, macrophages, neutrophils, blood vessel sections and thickness of the regenerating epithelium and dermis on days 4, 7 and 14. Re-epithelialization and angiogenesis were significantly improved in Aloe vera gel group compared with the other treatments while thyroid hormone cream had positive effects on day 4 (P¡Â0.05). Topical administration of Aloe vera gel is recommended as the treatment of choice for surgical incisions.
KEYWORD
Wound healing, Aloe, Thyroid hormones, Silver sulfadiazine, Wistar rats
FullTexts / Linksout information
  
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed